THE ROLE OF CHROMOSOME ANALYSIS IN MALE AND FEMALE INFERTILITY

Objective: Infertility is defined as absence of a healthy baby or pregnancy despite one-year regular unprotected sexual intercourse. While primary infertility called the at all, secondary inability couples who have had least one child to become pregnant. Chromosome anomalies are an important cause both male and female infertility. In this study, we aimed discuss results chromosome analysis with infertility.Material Methods: A total 535 people, 262 women 273 spouses infertility, were included in study. was performed using standard cytogenetic GTG banding technique peripheral blood lymphocytes.Results: Normal establishment detected 513 46,XX 254 46,XY 259 people (95.8%). Eight patients normal variant (1.4%). addition, translocation 5 (0.8%); 4 patients, balanced reciprocal 1 patient, Robertsonian translocation. Klinefelter syndrome 3 (1% infertility). Turner variants, mos 45,X[11]/46,XX,i (X)(q10)[29] 45,X[10]/46,X,i(X)(q10)[10] (0.7% infertility) two cases. If variants excluded, frequency remaining changes patient population 2.6%.Conclusion: Structural chromosomal such translocations 47,XXY should be kept mind for 45,X/46,X,i(X)(q10) summary, tests that done explain etiology